Everything changed after the break with Son latching onto another Kane through ball in the 47th minute to put his side ahead, before adding two more in the 64th and 74th minutes.
Saturday ends with Southampton facing a tricky visit to play Burnley. Southampton have lost both league games so far and were dumped out of the Carabao Cup by Brentford, while Burnley lost their only league game away to Leicester City, before bouncing back to beat Milwall in the Carabao Cup. They have a good record against Southampton with four wins and three draws against them since October 2016.
In the Meizhou division, Zhejiang Energy Greentown conceded a late goal for a 2-2 draw with Meizhou Hakka, while Jiangxi Lianshen defeated Liaoning Shengyang Urban 1-0, and Guizhou Hengfeng beat Shaanxi Chang'an Athletic 1-0.
Martinez is unlikely to make many changes to the side that beat Alaves on Sunday with Darwin Machis and Roberto Soldado leading the attack, while veteran striker Jorge Molina will also play a part at some point in the game.
Lokomotiv also have the advantage that the season in Georgia is more advanced than in Spain and they currently lie in fifth position in their domestic league with four wins, four draws and three defeats from 11 matches.
Danny Ings put Southampton ahead after half an hour and Spurs looked slow until Son equalized after an assist from Harry Kane two minutes into first half injury time.
BUDAPEST, Sept. 24 (Xinhua) -- Bayern Munich beat Sevilla 2-1 in an epic battle for the UEFA Super Cup that lasted 120 minutes here on Thursday.
The amended plans, now submitted to Liverpool City Council, respond to the site's location in a Unesco WHS and now include the introduction of a stepped plaza offering a new covered area for stadium entry and enhanced river views.
Bayern then reestablished control of the game, but Robert Lewandowski and Leroy Sane both had goals chalked off.
"The Club has informed the relevant authorities and the player has been promptly placed in quarantine at home. All other team members and staff have tested negative," it added.
Kulusevski put Juve in charge in the first half, while Leonardo Bonucci and Ronaldo sealed matters after the break.